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Cornell University    
  Jan 20, 2018
Courses of Study 2014-2015 [ARCHIVED CATALOG]

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ANSC 4300 - Comparative Genomics of Health and Disease in Domesticated Animals

Spring. (Offered alternate years) 2 credits. Letter grades only.

Prerequisite: ANSC 2210  or BIOMG 2800 .

S. Brooks.

As we approach the age of the “$1000” genome the number of mammals with at least a draft reference genome sequence is rapidly increasing. This is particularly true for large domesticated mammals like the horse, cattle, dog, pig and sheep. Genomic research in large animals, rather than traditional laboratory species, opens up new horizons in diversity of phenotype, mechanisms and technique. Through research papers we will explore recent discoveries that have both practical application and notable scientific implications. Concepts covered will include the impact of domestication on the genome, use of animals as models, genome wide mapping, chromosome evolution and structural variation. Students will be expected to present interesting findings to the class and participating in discussion.

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