VETMM 7070 - Protein NMR Spectroscopy

(crosslisted) BIOMG 7300

Spring (offered alternate years). 2 credits.

Prerequisite: CHEM 3890 and CHEM 3900 or CHEM 2870 and CHEM 2880 or permission of instructor.

R. E. Oswald, K. L. Nicholson.

The student acquires the tools necessary for in-depth understanding of multidimensional, multinuclear NMR experiments. Schemes for magnetization transfer, selective excitation, water suppression, decoupling, and others are presented. The application of these techniques to proteins for resonance assignments, structure determination, and dynamics characterization is studied.