Courses of Study 2013-2014 
    
    Mar 28, 2024  
Courses of Study 2013-2014 [ARCHIVED CATALOG]

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BIONB 4900 - Molecular, Cellular, and Integrative Neurophysiology


(PBS)
Fall. 4 credits. Letter grades only.

Prerequisite: BIONB 2220  or equivalent, or permission of instructor. Limited to 12 students. 

D. P. McCobb.

Hands-on lab with lecture/discussions introducing cellular and integrative electrophysiological concepts and methods.  Intra- and extracellular recording of action potentials, synaptic transmission, voltage clamp and ion channel gating, and interactions between autonomic function and cognition in humans.  Lectures will discuss concepts, recent discoveries, and future prospects.  Written and oral presentations required.

Outcome 1: First-hand expertise in the use of experimental methods for detecting and analyzing neural signals.

Outcome 2: Ability to identify and quantify extracellular, intracellular, and voltage clamp recordings and distinguish between real signals and artifacts or distortions.

Outcome 3: Appreciation for the diversity of intrinsic excitability, its underlying ion channel and molecular bases, and its central role in diverse information processing functions in the brain and body.

Outcome 4: Understanding of some aspects of synaptic function and plasticity, and their measurement.

Outcome 5: Appreciation for the role of the modulation of excitability and synaptic function to behavioral plasticity and adaptation.

Outcome 6: Skill in envisioning and designing experiments to extend our knowledge of neurophysiological mechanisms.

Outcome 7: Improved written documentation of experimental results, and more general written and oral communication in this field.



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