Courses of Study 2020-2021 
    
    Jun 25, 2021  
Courses of Study 2020-2021
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BME 6130 - Engineering the Microbiome


     
Fall. 3 credits. Letter grades only.

Prerequisite: BME 3020  and CS 1110 , or equivalents.

I. Brito.

The human microbiome impacts human health in a multitude of ways. To achieve a specific health outcome, we can modify the compositions of the microbiome, the molecules microbes produce, how they interact or how our body interacts with them. Yet, our current toolbox is fairly limited. In this course, we will examine current methods for intervening in the microbiome, but focus primarily on cutting-edge technologies for microbiome-related therapeutics. This will include synthetic biology and genetic engineering approaches. Topics will include: probiotics, antibiotics, drug discovery, live bacterial therapeutics, biosensors, phage therapies, bacterial evolution and engineering immune responses. We will touch on the safety implications of using different biological technologies. This course is designed for graduate students or Masters and advanced undergraduate students (with advanced permission). There will be a computational component to this course, although no prior computational experience is required.



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