VETMM 7070 - Protein NMR Spectroscopy

(crosslisted)
(also BIOMG 7300)

Spring. (Offered alternate years) 2 credits. S–U or letter grade option.

Prerequisite: CHEM 3890 and CHEM 3900 or CHEM 2870 and CHEM 2880 or permission of instructor. Next offered 2012-2013.

R. E. Oswald and K. L. Nicholson.

The student acquires the tools necessary for in-depth understanding of multidimensional, multinuclear NMR experiments. Schemes for magnetization transfer, selective excitation, water suppression, decoupling, and others are presented. The application of these techniques to proteins for resonance assignments, structure determination, and dynamics characterization is studied.