Courses of Study 2022-2023 
    
    Mar 28, 2024  
Courses of Study 2022-2023 [ARCHIVED CATALOG]

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BIOMS 6110 - Genome Maintenance Mechanisms


     
Fall. 1 credit. Student option grading.

Prerequisite: BIOMG 2800 , BIOMG 2801 , BIOMG 3300 , BIOMG 3310 , BIOMG 3330, or BIOMG 3350 .

R. Weiss.

This course focuses on the molecular mechanisms for preserving genomic integrity in eukaryotes. Topics discussed include: sources of mutation, DNA repair, and cell cycle checkpoints. Also addressed is how genome maintenance impacts genome plasticity and evolution, as well as the relationship between genomic instability and disease, including cancer.

Outcome 1: Have an awareness of the various manifestations of genomic instability and how different genetic alterations can impact gene function.

Outcome 2: Understand how mutations arise, as well as how defects in genome maintenance mechanisms can result in genomic instability.

Outcome 3: Be familiar with how cells respond to and repair genome damage.

Outcome 4: Possess the ability to critically read primary scientific publications.



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