BIOG 2045 - Introduction to Human Genetics

(OPHLS-AG)

Spring. 2 credits. Student option grading.

Offered in Doha, Qatar at Weill Cornell Medical College.

D. Lorenzetti.

This undergraduate course focuses on fundamental principles of Mendelian inheritance, applied to the genetic characterization of human diseases. The topics covered include patterns of inheritance for Mendelian human traits, mapping and identification of gene variants and mutations in humans. Elements of cancer genetics, as well as some general principles of genetic testing and counseling are discussed. Aims of the course a) to explore fundamental concepts of inheritance (i.e. structure and function of the genetic material, basic Mendelian genetics principles, mitotic and meiotic cell divisions, control of the cell cycle phases) b) to develop a basic knowledge of Mendelian modes of inheritance in humans, Mutation, Variation in humans and genetic testing, Chromosomal basis of human disease, and Cancer genetics.

Outcome 1: Students will be able to explain biology of blood and related organs in both health and diseases.

Outcome 2: Students will be able to explain the role of genetics and environment in the development of pathological processes.

Outcome 3: Students will be able to explain the basis of laboratory tests that apply in diagnosis as well as the foundation of the current targeted therapies.