BIOMS 6110 - [Genome Maintenance Mechanisms]

Fall. 1 credit. S-U or letter grade option.

Prerequisite: BIOMG 2810, as well as BIOMG 3300, BIOMG 3310, BIOMG 3330, or BIOMG 3350. Next offered 2012-2013.

R. Weiss.

This course focuses on the molecular mechanisms for preserving genomic integrity in eukaryotes. Topics discussed include sources of mutation, DNA repair, and cell cycle checkpoints. Also addressed is how genome maintenance impacts genome plasticity and evolution, as well as the relationship between genomic instability and disease, including cancer.