BME 3010 - Cellular Principles of Biomedical Engineering

Fall. 3 credits. Letter grades only.

Prerequisite: BIOMG 1350, or BIOG 1440 and BIOG 1445, or BIOMG 3300 and MATH 2930, or permission of instructor. Enrollment preference given to: BME majors.

S.D. Archer, M. Saikia.

This course will provide students a fundamental understanding of cellular systems essential for engineering effective biomedical applications. The course comprises of three modules.

Module 1 will discuss the principles of engineering, biology, chemistry, and mathematics that govern cell survival, growth and propagation. Mathematical models will be used to explain normal and tumor cell growth, cell signaling, cell cycle, and circadian rhythms. Students will learn mammalian cell culture techniques and create their own growth curves in the lab.

Module 2 will discuss how cells organize into multicellular tissue and organs within the human body. Characteristics of different cell types found within human body will be analyzed with special emphasis on stem cells and their application in tissue engineering.

Module 3 will discuss how cells react to environmental stimuli such as infection and injury. This module will also discuss interaction of living systems (cells) with non- living systems (implants) focusing on blood material interaction processes such as wound repair and coagulation. Students will explore stimulus driven cell migration in the lab.